发布日期：2024-04-16 16:02 浏览次数：
| 名称： | anti- PCNA antibody |
|---|---|
| 货号： | FNab06215 |
| 适应种属： | 人源,大鼠,小鼠 |
| 规格： | 100ug(微克) |
| 状态： | 液体 |
| 纯化方法： | 免疫亲和纯化 |
| 纯度： | 经SDS-PAGE分析,纯度大于95% |
| 宿主： | 兔 |
| 亚型： | lgG |
| 存储： | 用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月（避免反复冻融） |
| 免疫原： | proliferating cell nuclear antigen |
| 免疫原别称： | Proliferating cell nuclear antigen antibody, Cyclin antibody |
| 分子量： | 38 kDa |
| 验证应用： | ELISA, WB, IHC |
| 建议稀释比例： | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
| UniProt ID： | P12004 |
| 克隆性： | 多克隆 |
| 背景介绍： | The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. |
| 图像： |  Immunohistochemistry of paraffin-embedded human stomach cancer using FNab06215(PCNA antibody) at dilution of 1:50。  A431 cells were subjected to SDS PAGE followed by western blot with FNab06215(PCNA antibody) at dilution of 1:1000。 |