发布日期：2023-09-26 15:17 浏览次数：
|anti- TSG101 antibody
|tumor susceptibility gene 101
|ESCRT I complex subunit TSG101 antibody, TSG10 antibody, TSG101 antibody, tumor susceptibility gene 101 antibody, VPS23 antibody
|ELISA, WB, IHC
|WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
|The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using FNab09040( TSG101 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9)。