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抗HSP90抗体

发布日期:2023-09-26 16:02 浏览次数:

  • 英文名称: anti- HSP90 antibody
  • 产品货号: FNab04051
  • 适应种属:人源,大鼠,小鼠
  • 宿主:兔
  • 亚型:lgG
  • 验证应用: ELISA, IF, IHC, IP, WB, FC
  • 简介:菲恩生物抗HSP90抗体经SDS-PAGE分析,纯度大于95%,采用免疫亲和纯化方法,为用户提供高亲和力、高特异性的优质抗体。
    产品详情
    名称: anti- HSP90 antibody
    货号: FNab04051
    适应种属:人源,大鼠,小鼠
    规格:100ug(微克)
    状态:液体
    纯化方法:免疫亲和纯化
    纯度:经SDS-PAGE分析,纯度大于95%
    宿主:
    亚型:lgG
    存储:用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月(避免反复冻融)
    免疫原: heat shock protein 90kDa alpha(cytosolic), class A member 1
    免疫原别称: HSP 86 antibody, HSP86 antibody, Hsp89 antibody, HSP89A antibody, HSP90 antibody, HSP90A antibody, HSP90AA1 antibody, HSP90N antibody, HSPC1 antibody, HSPCA antibody, HSPCAL1 antibody, HSPCAL4 antibody, HSPN antibody, LAP2 antibody
    分子量: 90 kDa
    验证应用: ELISA, IF, IHC, IP, WB, FC
    建议稀释比例: WB: 1:1000-1:6000IP:1:500-1:1000 IHC: 1:20-1:200 IF: 1:10-1:100
    UniProt ID: P07900
    克隆性:多克隆
    背景介绍:HSP90, encoded by HSP90AA1, is a constitutively and ubiquitously expressed molecular chaperone that is crucial for the stability and function of many proteins. HSP90 provides chaperoning activity for client proteins; many of them are members of oncogenic pathways, indicating its implication in tumor malignancy. HSP90 mainly resides in the cytosol, while it can also be released to the extracellular space. Secreted Hsp90 is a C-terminal truncated form. It has been reported that the level of plasma Hsp90 is positively correlated with tumor malignancy in clinical cancer patients, and can be a promising diagnostic marker for tumor malignancy in clinical application.
    图像:HSP90抗体
    Immunohistochemistry of paraffin-embedded human liver cancer using FNab04051(HSP90 antibody) at dilution of 1:50。

         anti- HSP90 antibody
    IP Result of anti-HSP90 (IP: FNab04051, 4ug; Detection: FNab04051 1:500) with K-562 cells lysate 4000ug。


         anti- HSP90 antibody
    HeLa cells were subjected to SDS PAGE followed by western blot with FNab04051(HSP90 Antibody) at dilution of 1:3000。