发布日期：2023-11-10 09:59 浏览次数：
| 名称： | anti- CD3 epsilon antibody |
|---|---|
| 货号： | FNab01459 |
| 适应种属： | 人源 |
| 规格： | 100ug(微克) |
| 状态： | 液体 |
| 纯化方法： | 蛋白A/G柱纯化 |
| 纯度： | 经SDS-PAGE分析,纯度大于95% |
| 宿主： | 小鼠 |
| 亚型： | IgG1 |
| 存储： | 用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月（避免反复冻融） |
| 免疫原： | CD3e molecule, epsilon (CD3-TCR complex) |
| 免疫原别称： | CD3 antibody, CD3 epsilon antibody, CD3E antibody, CD3-epsilon antibody, T3E antibody, TCRE antibody |
| 分子量： | 23 kDa |
| 验证应用： | ELISA, WB, IHC, IF, FC |
| 建议稀释比例： | WB: 1:2000 - 1:20000; IHC: 1:1000 - 1:10000; IF: 1:50 - 500 |
| UniProt ID： | P07766 |
| 克隆性： | 单克隆 |
| 背景介绍： | CD3 is a complex of proteins that directly associates with the T cell receptor (TCR). The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction. CD3 is considered to be a pan-T cell marker for detection of normal and neoplastic T cells. This anti-CD3 is a monoclonal antibody directed against the epsilon chain of human CD3 molecule. |
| 图像： |  Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab01459( CD3E Antibody) at dilution of 1:8000。
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