发布日期：2024-01-26 10:02 浏览次数：
| 名称： | anti- CD86 antibody |
|---|---|
| 货号： | FNab01504 |
| 适应种属： | 人源,大鼠,小鼠 |
| 规格： | 100ug(微克) |
| 状态： | 液体 |
| 纯化方法： | 免疫亲和纯化 |
| 纯度： | 经DSD-PAGE分析,纯度大于95% |
| 宿主： | 兔 |
| 亚型： | lgG |
| 存储： | 用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月（避免反复冻融） |
| 免疫原： | CD86 molecule |
| 免疫原别称： | Activation B7 2 antigen antibody, B7 2 antibody, B70 antibody, BU63 antibody, CD28LG2 antibody, CD86 antibody, CD86 molecule antibody, CTLA 4 counter receptor B7.2 antibody, FUN 1 antibody, LAB72 antibody |
| 分子量： | 75 kDa |
| 验证应用： | ELISA, WB,IHC,IF |
| 建议稀释比例： | WB: 1:200-1:2000; IHC: 1:50-1:500; IF: 1:20-1:200 |
| UniProt ID： | P42081 |
| 克隆性： | 多克隆 |
| 背景介绍： | Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.(Microbial infection) Acts as a receptor for adenovirus subgroup B. |
| 图像： |  Immunofluorescent analysis of RAW264.7 cells using FNab01504 ( CD86 Antibody) at dilution of 1:50。  Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab01504(CD86 Antibody) at dilution of 1:200. heat mediated antigen retrieved with Tris-EDTA buffer(pH9)。  Jurkat cells were subjected to SDS PAGE followed by western blot with FNab01504(CD86 antibody) at dilution of 1:500。 |