发布日期：2024-02-04 16:01 浏览次数：
| 名称： | anti- N-cadherin antibody |
|---|---|
| 货号： | FNab05571 |
| 适应种属： | 人源,大鼠,小鼠 |
| 规格： | 100ug(微克) |
| 状态： | 液体 |
| 纯化方法： | 蛋白A/G柱纯化 |
| 纯度： | 经SDS-PAGE分析,纯度大于95% |
| 宿主： | 小鼠 |
| 亚型： | IgG2a |
| 存储： | 用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月（避免反复冻融） |
| 免疫原： | cadherin 2, type 1, N-cadherin(neuronal) |
| 免疫原别称： | Cadherin 2 antibody, CD325 antibody, CDH2 antibody, CDHN antibody, CDw325 antibody, N cadherin antibody, NCAD antibody, N-cadherin antibody, Neural cadherin antibody |
| 分子量： | 130 kDa |
| 验证应用： | ELISA, IHC, WB |
| 建议稀释比例： | WB: 1:1000-1:10000; IHC: 1:20-1:200 |
| UniProt ID： | P19022 |
| 克隆性： | 单克隆 |
| 背景介绍： | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density(By similarity). |
| 图像： |  Immunohistochemistry of paraffin-embedded human heart tissue slide using FNab05571(N-cadherin Antibody) at dilution of 1:200。  human heart tissue were subjected to SDS PAGE followed by western blot with FNab05571(N-cadherin Antibody) at dilution of 1:2000。 |