发布日期:2023-11-10 10:12 浏览次数:
名称: | anti- CD8 antibody |
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货号: | FNab10807 |
适应种属: | 人源 |
规格: | 100ug(微克) |
状态: | 液体 |
纯化方法: | 蛋白A/G柱纯化 |
纯度: | 经SDS-PAGE分析,纯度大于95% |
宿主: | 小鼠 |
亚型: | IgG1 |
存储: | 用添加了0.02%叠氮化钠和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12个月(避免反复冻融) |
免疫原: | CD8a molecule |
免疫原别称: | CD8 antibody, Leu2 antibody, MAL antibody, p32 antibody |
分子量: | 30 kDa |
验证应用: | ELISA, WB, IHC |
建议稀释比例: | WB: 1:500 - 1:2000; IHC: 1:500 - 1:2000 |
UniProt ID: | P01732 |
克隆性: | 单克隆 |
背景介绍: | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. |
图像: | Immunohistochemistry of paraffin-embedded human breast cancer using FNab10807(CD8 antibody) at dilution of 1:1000。
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